CCQM-K55.d : Mass fraction of Folic acid and impurity assessment
MEASURAND : Mass fraction of Folic acid in CCQM-K55.d samples
Degrees of equivalence : offset Di and expanded uncertainty (k = 2) Ui expressed in mg/g, and also in relative terms
CCQM-K55.d : Mass fraction of Folic acid and impurity assessment
MEASURAND : Mass fraction of total related structure impurity content in CCQM-K55.d samples
Degrees of equivalence : offset Di and expanded uncertainty (k = 2) Ui expressed in mg/g, and also in relative terms
CCQM-K55.d : Mass fraction of Folic acid and impurity assessment
MEASURAND : Mass fraction of Water in CCQM-K55.d samples
Degrees of equivalence : offset Di and expanded uncertainty (k = 2) Ui expressed in mg/g, and also in relative terms
CCQM-K55.d : Mass fraction of Folic acid and impurity assessment
MEASURAND : Mass fraction of Volatile organic content in CCQM-K55.d samples
Degrees of equivalence : offset Di and expanded uncertainty (k = 2) Ui expressed in mg/g, and also in relative terms
CCQM-K55.d : Mass fraction of Folic acid and impurity assessment
MEASURAND : Mass fraction of Non-volatile content in CCQM-K55.d samples
Degrees of equivalence : offset Di and expanded uncertainty (k = 2) Ui expressed in mg/g, and also in relative terms
CCQM-K55.d : Mass fraction of Folic acid and impurity assessment
MEASURAND : Mass fraction of Folic acid in CCQM-K55.d samples
Degrees of equivalence : offset Di and expanded uncertainty (k = 2) Ui expressed in mg/g
xR = 906.5 mg/g and 2 uR = 9.6 mg/g
Results are presented under A4 printable format in Summary Results (PDF file).
CCQM-K55.d : Mass fraction of Folic acid and impurity assessment
MEASURAND : Mass fraction of total related structure impurity content in CCQM-K55.d samples
Degrees of equivalence : offset Di and expanded uncertainty (k = 2) Ui expressed in mg/g
xR = 12.6 mg/g and 2 uR = 6.2 mg/g
Results are presented under A4 printable format in Summary Results (PDF file).
CCQM-K55.d : Mass fraction of Folic acid and impurity assessment
MEASURAND : Mass fraction of Water in CCQM-K55.d samples
Degrees of equivalence : offset Di and expanded uncertainty (k = 2) Ui expressed in mg/g
xR = 78.0 mg/g and 2 uR = 3.2 mg/g
Results are presented under A4 printable format in Summary Results (PDF file).
CCQM-K55.d : Mass fraction of Folic acid and impurity assessment
MEASURAND : Mass fraction of Volatile organic content in CCQM-K55.d samples
Degrees of equivalence : offset Di and expanded uncertainty (k = 2) Ui expressed in mg/g
xR = 0.374 mg/g and 2 uR = 0.166 mg/g
Results are presented under A4 printable format in Summary Results (PDF file).
CCQM-K55.d : Mass fraction of Folic acid and impurity assessment
MEASURAND : Mass fraction of Non-volatile content in CCQM-K55.d samples
Degrees of equivalence : offset Di and expanded uncertainty (k = 2) Ui expressed in mg/g
xR = 0.3 mg/g and 2 uR = 0.4 mg/g
Results are presented under A4 printable format in Summary Results (PDF file).
| Metrology area, Sub-field | Chemistry and Biology, Organics |
| Description | Purity assessment of high purity organic materials: Folic acid |
| Time of measurements | 2015 - 2016 |
| Status | Approved for equivalence |
| Final Reports of the comparisons | |
| References | |
| Measurand | Mass fraction in mg/g of Folic Acid in a sample. Nominal value in excess of 900 mg/g Required: Mass fraction content of main component Optional: Mass fraction content of impurities |
| Transfer device | Crimp-sealed amber glass vial containing 500 mg of the CCQM-K55.d comparison material as a crystalline powder. |
| Comparison type | Key Comparison |
| Consultative Committee | CCQM (Consultative Committee for Amount of Substance) |
| Conducted by | CCQM (Consultative Committee for Amount of Substance) |
| Comments | Results published on 14 May 2018 Purity assessment of high purity organic materials: Folic acid
|
| Pilot institute |
BIPM
Bureau International des Poids et Mesures BIPM - International Organization |
| Contact person | Steven Westwood +33 (0) 1 45 07 70 57 |
| Pilot laboratory | |
|---|---|
| BIPM |
Bureau International des Poids et Mesures, BIPM - International Organization, N/A |
| BAM |
Bundesanstalt für Materialforschung und -prüfung, Germany, EURAMET |
| CENAM |
Centro Nacional de Metrologia, Mexico, SIM |
| GL |
Government Laboratory, Hong Kong, China, APMP |
| HSA |
Health Science Authority, Singapore, APMP |
| INMETRO |
Instituto Nacional de Metrologia, Qualidade e Tecnologia, Brazil, SIM |
| KRISS |
Korea Research Institute of Standards and Science, Korea, Republic of, APMP |
| LGC |
Laboratory of the Government Chemist, United Kingdom, EURAMET |
| NIM |
National Institute of Metrology, China, APMP |
| NIMT |
National Institute of Metrology (Thailand), Thailand, APMP |
| NIST |
National Institute of Standards and Technology, United States, SIM |
| NMIA |
National Measurement Institute, Australia, Australia, APMP |
| NMIJ AIST |
National Metrology Institute of Japan, Japan, APMP |
| NMISA |
National Metrology Institute of South Africa, South Africa, AFRIMETS |
| NRC |
National Research Council, Canada, SIM |
| UME |
TÜBITAK Ulusal Metroloji Enstitüsü, Türkiye, EURAMET |
| VNIIM |
D.I. Mendeleyev Institute for Metrology, Rosstandart, Russian Federation, COOMET |
This page proposes print-out on A4 paper (portrait) of the comparison details (best printed out using a black and white printer).
Please, select items to be printed out, then click on "OK" :
CCQM-K55.d : Mass fraction of Folic acid and impurity assessment
MEASURAND : Mass fraction of Folic acid in CCQM-K55.d samples
|
The key comparison reference values , xR, and associated standard uncertainty (uR) were assigned for the mass fraction of the following impurity classes: total related structure impurity content, water, volatile organic content and non-volatile content. They are consensus values derived from the individual data supplied by each participant. Folic acid: xR = 906.5 mg/g uR = 4.8 mg/g Total impurity content: xR = 12.6 mg/g uR = 3.1 mg/g Water: xR = 78.0 mg/g uR = 1.6 mg/g Volatile organic content: xR = 0.374 mg/g uR = 0.083 mg/g Non-volatile content: xR = 0.3 mg/g uR = 0.2 mg/g
|
| The degree of equivalence of laboratory i with respect to the key comparison reference value is given by a pair of terms: Di = (xi - xR) and Ui, its expanded uncertainty (k = 2), both expressed in mg/g, with Ui = 2(ui2 + uR2)1/2. |
CCQM-K55.d : Mass fraction of Folic acid and impurity assessment
MEASURAND : Mass fraction of total related structure impurity content in CCQM-K55.d samples
|
The key comparison reference values , xR, and associated standard uncertainty (uR) were assigned for the mass fraction of the following impurity classes: total related structure impurity content, water, volatile organic content and non-volatile content. They are consensus values derived from the individual data supplied by each participant. Folic acid: xR = 906.5 mg/g uR = 4.8 mg/g Total impurity content: xR = 12.6 mg/g uR = 3.1 mg/g Water: xR = 78.0 mg/g uR = 1.6 mg/g Volatile organic content: xR = 0.374 mg/g uR = 0.083 mg/g Non-volatile content: xR = 0.3 mg/g uR = 0.2 mg/g
|
| The degree of equivalence of laboratory i with respect to the key comparison reference value is given by a pair of terms: Di = (xi - xR) and Ui, its expanded uncertainty (k = 2), both expressed in mg/g, with Ui = 2(ui2 + uR2)1/2. |
CCQM-K55.d : Mass fraction of Folic acid and impurity assessment
MEASURAND : Mass fraction of Water in CCQM-K55.d samples
|
The key comparison reference values , xR, and associated standard uncertainty (uR) were assigned for the mass fraction of the following impurity classes: total related structure impurity content, water, volatile organic content and non-volatile content. They are consensus values derived from the individual data supplied by each participant. Folic acid: xR = 906.5 mg/g uR = 4.8 mg/g Total impurity content: xR = 12.6 mg/g uR = 3.1 mg/g Water: xR = 78.0 mg/g uR = 1.6 mg/g Volatile organic content: xR = 0.374 mg/g uR = 0.083 mg/g Non-volatile content: xR = 0.3 mg/g uR = 0.2 mg/g
|
| The degree of equivalence of laboratory i with respect to the key comparison reference value is given by a pair of terms: Di = (xi - xR) and Ui, its expanded uncertainty (k = 2), both expressed in mg/g, with Ui = 2(ui2 + uR2)1/2. |
CCQM-K55.d : Mass fraction of Folic acid and impurity assessment
MEASURAND : Mass fraction of Volatile organic content in CCQM-K55.d samples
|
The key comparison reference values , xR, and associated standard uncertainty (uR) were assigned for the mass fraction of the following impurity classes: total related structure impurity content, water, volatile organic content and non-volatile content. They are consensus values derived from the individual data supplied by each participant. Folic acid: xR = 906.5 mg/g uR = 4.8 mg/g Total impurity content: xR = 12.6 mg/g uR = 3.1 mg/g Water: xR = 78.0 mg/g uR = 1.6 mg/g Volatile organic content: xR = 0.374 mg/g uR = 0.083 mg/g Non-volatile content: xR = 0.3 mg/g uR = 0.2 mg/g
|
| The degree of equivalence of laboratory i with respect to the key comparison reference value is given by a pair of terms: Di = (xi - xR) and Ui, its expanded uncertainty (k = 2), both expressed in mg/g, with Ui = 2(ui2 + uR2)1/2. |
CCQM-K55.d : Mass fraction of Folic acid and impurity assessment
MEASURAND : Mass fraction of Non-volatile content in CCQM-K55.d samples
|
The key comparison reference values , xR, and associated standard uncertainty (uR) were assigned for the mass fraction of the following impurity classes: total related structure impurity content, water, volatile organic content and non-volatile content. They are consensus values derived from the individual data supplied by each participant. Folic acid: xR = 906.5 mg/g uR = 4.8 mg/g Total impurity content: xR = 12.6 mg/g uR = 3.1 mg/g Water: xR = 78.0 mg/g uR = 1.6 mg/g Volatile organic content: xR = 0.374 mg/g uR = 0.083 mg/g Non-volatile content: xR = 0.3 mg/g uR = 0.2 mg/g
|
| The degree of equivalence of laboratory i with respect to the key comparison reference value is given by a pair of terms: Di = (xi - xR) and Ui, its expanded uncertainty (k = 2), both expressed in mg/g, with Ui = 2(ui2 + uR2)1/2. |
CCQM-K55.d : Mass fraction of Folic acid and impurity assessment
MEASURAND : Mass fraction of Folic acid in CCQM-K55.d samples
xi : result of measurement carried out by laboratory i
ui : combined standard uncertainty of xi
CCQM-K55.d : Mass fraction of Folic acid and impurity assessment
MEASURAND : Mass fraction of total related structure impurity content in CCQM-K55.d samples
xi : result of measurement carried out by laboratory i
ui : combined standard uncertainty of xi
CCQM-K55.d : Mass fraction of Folic acid and impurity assessment
MEASURAND : Mass fraction of Water in CCQM-K55.d samples
xi : result of measurement carried out by laboratory i
ui : combined standard uncertainty of xi
CCQM-K55.d : Mass fraction of Folic acid and impurity assessment
MEASURAND : Mass fraction of Volatile organic content in CCQM-K55.d samples
xi : result of measurement carried out by laboratory i
ui : combined standard uncertainty of xi
CCQM-K55.d : Mass fraction of Folic acid and impurity assessment
MEASURAND : Mass fraction of Non-volatile content in CCQM-K55.d samples
xi : result of measurement carried out by laboratory i
ui : combined standard uncertainty of xi
