CCQM-K109

MEASURANDS : Urea and uric acid i two different serums

Urea : nominal mass fraction around 1500 mg/kg (higher than normal biological range)
 

Degrees of equivalence: Di = (xi - xR) and expanded uncertainty Ui at a 95 % level of confidence both expressed in mg/kg.

 

CCQM-K109

MEASURANDS : Urea and uric acid i two different serums

Urea : nominal mass fraction around 335 mg/kg (normal biological range)
 

Degrees of equivalence: Di = (xi - xR) and expanded uncertainty Ui at a 95 % level of confidence both expressed in mg/kg.

 

CCQM-K109

MEASURANDS : Urea and uric acid i two different serums

Uric acid : nominal mass fraction around 136 mg/kg (higher than normal biological range)

Degrees of equivalence: Di = (xi - xR) and expanded uncertainty Ui at a 95 % level of confidence both expressed in mg/kg.

 

CCQM-K109

MEASURANDS : Urea and uric acid i two different serums

Uric acid : nominal mass fraction around 39 mg/kg (normal biological range)

Degrees of equivalence: Di = (xi - xR) and expanded uncertainty Ui at a 95 % level of confidence both expressed in mg/kg.

 

CCQM-K109

MEASURANDS : Urea and uric acid i two different serums

Urea : nominal mass fraction around 1500 mg/kg (higher than normal biological range)
 

The table below gives the degrees of equivalence for participant laboratory i.

Results are presented under A4 printable format in Summary Results (.PDF file).

CCQM-K109

MEASURANDS : Urea and uric acid i two different serums

Urea : nominal mass fraction around 335 mg/kg (normal biological range)
 

The table below gives the degrees of equivalence for participant laboratory i.

Results are presented under A4 printable format in Summary Results (.PDF file).

CCQM-K109

MEASURANDS : Urea and uric acid i two different serums

Uric acid : nominal mass fraction around 136 mg/kg (higher than normal biological range)

The table below gives the degrees of equivalence for participant laboratory i.

Results are presented under A4 printable format in Summary Results (.PDF file).

CCQM-K109

MEASURANDS : Urea and uric acid i two different serums

Uric acid : nominal mass fraction around 39 mg/kg (normal biological range)

The table below gives the degrees of equivalence for participant laboratory i.

Results are presented under A4 printable format in Summary Results (.PDF file).

Comparison
Comparison close
CC comparison
Linked comparison
CCQM-K109
Metrology area, Sub-field Chemistry and Biology, Organics
Description Urea and uric acid in human serum
Time of measurements 2016
Status Approved for equivalence
Final Reports of the comparisons
References

CCQM-K109 Technical protocol

CCQM Registration and progress form

Measurand Mass fraction of urea (100 mg/kg - 2000 mg/kg) and uric acid (10 mg/kg - 165 mg/kg) in human serum
Transfer device Dedicated samples of human serum
Comparison type Key Comparison
Consultative Committee CCQM (Consultative Committee for Amount of Substance)
Conducted by CCQM (Consultative Committee for Amount of Substance)
Comments

Samples were distributed by the coordinating institute.

Results published on 30 January 2019

Urea and uric acid in two different serums

Pilot institute HSA
Health Science Authority
Singapore
Contact person Richard Shin

+65 6775 1605 (ext 103)
Additional
First Name Last Name
wwww@ww.www +356719836 Institute 1 Institute 1 Khmelnitskiy
Pilot laboratory
HSA

Health Science Authority, Singapore, APMP

CENAM

Centro Nacional de Metrologia, Mexico, SIM

GL

Government Laboratory, Hong Kong, China, APMP

INMETRO

Instituto Nacional de Metrologia, Qualidade e Tecnologia, Brazil, SIM

KRISS

Korea Research Institute of Standards and Science, Korea, Republic of, APMP

LGC

Laboratory of the Government Chemist, United Kingdom, EURAMET

LNE

Laboratoire national de métrologie et d'essais, France, EURAMET

NIM

National Institute of Metrology, China, APMP

NIMT

National Institute of Metrology (Thailand), Thailand, APMP

NIST

National Institute of Standards and Technology, United States, SIM

NMIA

National Measurement Institute, Australia, Australia, APMP

NMIJ AIST

National Metrology Institute of Japan, Japan, APMP

PTB

Physikalisch-Technische Bundesanstalt, Germany, EURAMET

UME

TÜBITAK Ulusal Metroloji Enstitüsü, Türkiye, EURAMET

VNIIM

D.I. Mendeleyev Institute for Metrology, Rosstandart, Russian Federation, COOMET

CCQM-K109

MEASURANDS : Urea and uric acid i two different serums

Urea : nominal mass fraction around 1500 mg/kg (higher than normal biological range)
 

The key comparison reference value xR and its associated standard uncertainty uR are computed from a Laplacian weighted median of the reported results, INMETRO and KRISS excluded.

                         xR = 1486.0 mg/kg      uR = 9.1 mg/kg

 

The degree of equivalence of laboratory i relative to the key comparison reference value is given by a pair of terms, both expressed in mg/kg:

Di = (xi - xR) and its expanded uncertainty Ui = 2 × ui

CCQM-K109

MEASURANDS : Urea and uric acid i two different serums

Urea : nominal mass fraction around 335 mg/kg (normal biological range)

The key comparison reference value xR and its associated standard uncertainty uR are computed from a Laplacian weighted median of the reported results, INMETRO and KRISS excluded.

                         xR = 334.7 mg/kg      uR = 1.8 mg/kg

 

The degree of equivalence of laboratory i relative to the key comparison reference value is given by a pair of terms, both expressed in mg/kg:

Di = (xi - xR) and its expanded uncertainty Ui = 2 × ui

CCQM-K109

MEASURANDS : Urea and uric acid i two different serums

Uric acid : nominal mass fraction around 136 mg/kg (higher than normal biological range)

 

The key comparison reference value xR and its associated standard uncertainty uR are computed from a Laplacian weighted median of the reported results, VNIIM, INMETRO, CENAM and KRISS excluded.

                         xR = 136.5 mg/kg      uR = 0.98 mg/kg

 

The degree of equivalence of laboratory i relative to the key comparison reference value is given by a pair of terms, both expressed in mg/kg:

Di = (xi - xR) and its expanded uncertainty Ui = 2 × ui

CCQM-K109

MEASURANDS : Urea and uric acid i two different serums

Uric acid : nominal mass fraction around 39 mg/kg (normal biological range)
 

The key comparison reference value xR and its associated standard uncertainty uR are computed from a Laplacian weighted median of the reported results, INMETRO, CENAM and KRISS excluded.

                         xR = 39.39 mg/kg      uR = 0.11 mg/kg

 

The degree of equivalence of laboratory i relative to the key comparison reference value is given by a pair of terms, both expressed in mg/kg:

Di = (xi - xR) and its expanded uncertainty Ui = 2 × ui

CCQM-K109

MEASURANDS : Urea and uric acid i two different serums

Urea : nominal mass fraction around 1500 mg/kg (higher than normal biological range)

xi: measured mass fraction by Labi
ui: combined standard uncertainty of xi

k: expansion factor
Ui: expanded uncertainty of xi at 95 % level of confidence where Ui = k ui

CCQM-K109

MEASURANDS : Urea and uric acid i two different serums

Urea : nominal mass fraction around 335 mg/kg (normal biological range)

xi: measured mass fraction by Labi
ui: combined standard uncertainty of xi

k: expansion factor
Ui: expanded uncertainty of xi at 95 % level of confidence where Ui = k ui

CCQM-K109

MEASURANDS : Urea and uric acid i two different serums

Uric acid : nominal mass fraction around 136 mg/kg (higher than normal biological range)

xi: measured mass fraction by Labi
ui: combined standard uncertainty of xi

k: expansion factor
Ui: expanded uncertainty of xi at 95 % level of confidence where Ui = k ui

CCQM-K109

MEASURANDS : Urea and uric acid i two different serums

Uric acid : nominal mass fraction around 39 mg/kg (normal biological range)

xi: measured mass fraction by Labi
ui: combined standard uncertainty of xi

k: expansion factor
Ui: expanded uncertainty of xi at 95 % level of confidence where Ui = k ui