Comparison
Comparison close

CCQM-K12 and CCQM-K12.2

MEASURAND : Mass fraction of creatinine in human serum
 

Degrees of equivalence Di and expanded uncertainty Ui (95% level of confidence) expressed in µg/g.


Red diamonds: CCQM-K12
Blue squares: CCQM-K12.2

CCQM-K12 and EURAMET.QM-K12

MEASURAND : Mass fraction of creatinine in human serum
Material II - elevated range

Degrees of equivalence Di and expanded uncertainty Ui (95% level of confidence) expressed in relative terms

Comparison
Comparison close

CCQM-K12 and CCQM-K12.2

MEASURAND : Mass fraction of creatinine in human serum
 

Degrees of equivalence Di and expanded uncertainty Ui (95% level of confidence) expressed in µg/g.


 

c

Information is available in Summary Results 

CCQM-K12 and EURAMET.QM-K12

MEASURAND : Mass fraction of creatinine in human serum
Material II : elevated range

Degrees of equivalence Di and expanded uncertainty Ui (95% level of confidence) expressed in relative terms

Dark blue indicates participants in CCQM-K12 (Material II)
Blue indicates participants in EURAMET.QM-K12 (Material A)
Green indicates participants in EURAMET.QM-K12 (Material B)

The degrees of equivalence expressed in µg/g, and the pair-wise degrees of equivalence expressed in µg/g given below are for participants in CCQM-K12 only.

   
Lab iDiUi
 / (µg/g) / (µg/g)
IRMM0.0750.487
KRISS-0.1060.331
LGC-0.0310.125
NIST0.0630.205
PTB0.0730.161

Results are presented under A4 printable format in Summary Results (PDF file).

Comparison
Comparison close
CC comparison
Linked comparison
CCQM-K12.2
Metrology area, Sub-field Chemistry and Biology, Organics
Description Creatinine in human serum
Time of measurements 2012
Status Approved for equivalence
Final Reports of the comparisons
Measurand Mass fraction
Transfer device Frozen serum materials
Comparison type Key Comparison
Consultative Committee CCQM (Consultative Committee for Amount of Substance)
Conducted by CCQM (Consultative Committee for Amount of Substance)
Comments

This is a subsequent key comparison to CCQM-K12.

Results published on 15 June 2018

Creatinine in human serum

CCQM-K12.2 results are linked to those of CCQM-K12 for Material I

(7 µg/g to 8 µg/g)

Pilot institute NIST
National Institute of Standards and Technology
United States
Contact person M.J. Welch

+1 301 975 3100
First Name Last Name
wwww@ww.www +356719836 Institute 1 Institute 1 Khmelnitskiy
Pilot laboratory
NIST

National Institute of Standards and Technology, United States, SIM

CENAM

Centro Nacional de Metrologia, Mexico, SIM

HSA

Health Science Authority, Singapore, APMP

INMETRO

Instituto Nacional de Metrologia, Qualidade e Tecnologia, Brazil, SIM

KRISS

Korea Research Institute of Standards and Science, Korea, Republic of, APMP

LNE

Laboratoire national de métrologie et d'essais, France, EURAMET

NIM

National Institute of Metrology, China, APMP

NIMT

National Institute of Metrology (Thailand), Thailand, APMP

NMIJ AIST

National Metrology Institute of Japan, Japan, APMP

PTB

Physikalisch-Technische Bundesanstalt, Germany, EURAMET

UME

TÜBITAK Ulusal Metroloji Enstitüsü, Türkiye, EURAMET

VNIIM

D.I. Mendeleyev Institute for Metrology, Rosstandart, Russian Federation, COOMET

Comparison
Comparison close

CCQM-K12 and CCQM-K12.2

MEASURAND : Mass fraction of creatinine in human serum

The key comparison reference value, xR, is calculated as the mean of the participants' results excluding IRMM: xR = 8.217 µg/g.
The expanded uncertainty of the key comparison reference value at a 95% level of confidence is: UR = 0.066 µg/g.

The degree of equivalence of each laboratory with respect to the key comparison reference value is given by a pair of terms: Di = (xi - xR) and Ui, its expanded uncertainty corresponding to a 95% level of confidence, both expressed in µg/g.

 

Linking CCQM-K12.2 to CCQM-K12

An independent key comparison reference value was assigned from the mean, standard deviation, and pooled standard uncertainty of the results reported by the three reference laboratories KRISS, NIST and PTB and the participants.

CCQM-K12 and EURAMET.QM-K12

  • Key comparison CCQM-K12

MEASURAND : Mass fraction of creatinine in human serum
Material II - elevated range

The key comparison reference value, xR, is calculated as the mean of the participants' results excluding IRMM: xR = 18.645 µg/g.
The expanded uncertainty of the key comparison reference value at a 95% level of confidence is: UR = 0.135 µg/g.

The degree of equivalence of each laboratory with respect to the key comparison reference value is given by a pair of terms: Di = (xi - xR) and Ui, its expanded uncertainty corresponding to a 95% level of confidence, both expressed in µg/g.
Di and Ui are also given here in relative terms.

The degree of equivalence between two laboratories is given by a pair of terms:
Dij = Di - Dj = (xi - xR) - (xj - xR) = (xi - xj) and Uij, its expanded uncertainty corresponding to a 95% level of confidence, both expressed in µg/g.
  • Linking EURAMET.QM-K12 to CCQM-K12

The linkage is obtained through the common participation of PTB and LGC in both key comparisons and is explained on page 14 of the EURAMET.QM-K12 Final Report.
The set of results obtained for Material II in CCQM-K12 was used to link the results obtained for both material A and B in EURAMET.QM-K12, as this was closer in nominal mass fraction. It leads to the computation of the degrees of equivalence of participants in EURAMET.QM-K12 relative to the CCQM-K12 reference value.
The Di and Ui values are given in relative terms.

No pair-wise degrees of equivalence involving participants in EURAMET.QM-K12 only have been computed.

Comparison
Comparison close

CCQM-K12 and CCQM-K12.2

MEASURAND : Mass fraction of creatinine in human serum
 

xi : result of measurement carried out by laboratory i
ui
: combined standard uncertainty of xi

CCQM-K12

CCQM-K12.2

CCQM-K12 and EURAMET.QM-K12

  • Key comparison CCQM-K12

MEASURAND : Mass fraction of creatinine in human serum
Material II - elevated range

xi : result of measurement carried out by laboratory i
ui
: combined standard uncertainty of xi

  • Key comparison EURAMET.QM-K12

MEASURAND : Mass fraction of creatinine in human serum

xi-EUR : result of measurement carried out by laboratory i participating in EURAMET.QM-K12
ui-EUR : combined standard uncertainty of xi-EUR

Material A - high level

Material B - low level