MEASURAND : Mass fraction of Valine in the CCQM-K55.c samples

Degrees of equivalence : offset Di and expanded uncertainty (k = 2) Ui expressed in mg/g, and also in relative terms

xR = 992.0 mg/g
2 uR = 0.6 mg/g

UCENAM = 112.76 mg/g

MEASURAND : Mass fraction of Related Structure Impurities in the CCQM-K55.c samples

Degrees of equivalence : offset Di and expanded uncertainty (k = 2) Ui expressed in mg/g, and also in relative terms

xR = 7.60 mg/g
2 uR = 0.48 mg/g

MEASURAND : Mass fraction of Water in the CCQM-K55.c samples

Degrees of equivalence : offset Di and expanded uncertainty (k = 2) Ui expressed in mg/g, and also in relative terms

xR = 0.155 mg/g
2 uR = 0.084 mg/g

MEASURAND : Mass fraction of Volatile Organics in the CCQM-K55.c samples

Degrees of equivalence : offset Di and expanded uncertainty (k = 2) Ui expressed in mg/g


xR = 0.0 mg/g and 2 uR+ = 0.24, 2 uR- = 0.0 mg/g

MEASURAND : Mass fraction of Non-Volatile Content in the CCQM-K55.bc samples

Degrees of equivalence : offset Di and expanded uncertainty (k = 2) Ui expressed in mg/g, and in relative terms


xR = 0.25 mg/g
2 uR = 0.288 mg/g

MEASURAND : Mass fraction of Valine in the CCQM-K55.c samples

Degrees of equivalence : offset Di and expanded uncertainty (k = 2) Ui expressed in mg/g

xR = 992.0 mg/g and 2 uR = 0.6 mg/g

Results are presented under A4 printable format in Summary Results (PDF file).

MEASURAND : Mass fraction of Related Structure Impurities in the CCQM-K55.c samples

Degrees of equivalence : offset Di and expanded uncertainty (k = 2) Ui expressed in mg/g
xR = 7.60 mg/g and 2 uR = 0.48 mg/g

Results are presented under A4 printable format in Summary Results (PDF file).

MEASURAND : Mass fraction of Water in the CCQM-K55.c samples

Degrees of equivalence : offset Di and expanded uncertainty (k = 2) Ui expressed in mg/g
xR = 0.155 mg/g and 2 uR = 0.084 mg/g

Results are presented under A4 printable format in Summary Results (PDF file).

MEASURAND : Mass fraction of Volatile Organics in the CCQM-K55.c samples

Degrees of equivalence : offset Di and expanded uncertainty (k = 2) Ui expressed in mg/g
xR = 0.0 mg/g and 2 uR+ = 0.24, 2 uR- = 0.0 mg/g

Results are presented under A4 printable format in Summary Results (PDF file).

MEASURAND : Mass fraction of Non-Volatile Content in the CCQM-K55.bc samples

Degrees of equivalence : offset Di and expanded uncertainty (k = 2) Ui expressed in mg/g
xR = 0.25 mg/g and 2 uR = 0.288 mg/g

Results are presented under A4 printable format in Summary Results (PDF file).

Comparison
Comparison close
CC comparison
Linked comparison
CCQM-K55.c
Metrology area, Sub-field Chemistry and Biology, Organics
Description Purity assessment of high purity organic materials: L-(+)-Valine
Time of measurements 2012
Status Approved for equivalence
Final Reports of the comparisons
Measurand Mass fraction in mg/g of L-(+)-Valine in the comparison sample
Transfer device Dedicated samples
Comparison type Key Comparison
Consultative Committee CCQM (Consultative Committee for Amount of Substance)
Conducted by CCQM (Consultative Committee for Amount of Substance)
Comments

If mass balance approach used, participants must also provide estimates of the mass fraction content of each sub-class of impurity contributing to the derived value for the main component.

Results published on 24 June 2014

Purity assessment of high purity organic materials: L-(+)-Valine

Pilot institute BIPM
Bureau International des Poids et Mesures
BIPM - International Organization
Contact person Steven Westwood

+33 (0) 1 45 07 70 57
First Name Last Name
wwww@ww.www +356719836 Institute 1 Institute 1 Khmelnitskiy
Pilot laboratory
BIPM

Bureau International des Poids et Mesures, BIPM - International Organization, N/A

BAM

Bundesanstalt für Materialforschung und -prüfung, Germany, EURAMET

CENAM

Centro Nacional de Metrologia, Mexico, SIM

GL

Government Laboratory, Hong Kong, China, APMP

HSA

Health Science Authority, Singapore, APMP

INMETRO

Instituto Nacional de Metrologia, Qualidade e Tecnologia, Brazil, SIM

IRMM

Institute for Reference Materials and Measurements, European Union, EURAMET

KRISS

Korea Research Institute of Standards and Science, Korea, Republic of, APMP

LGC

Laboratory of the Government Chemist, United Kingdom, EURAMET

LNE

Laboratoire national de métrologie et d'essais, France, EURAMET

NIM

National Institute of Metrology, China, APMP

NIMT

National Institute of Metrology (Thailand), Thailand, APMP

NIST

National Institute of Standards and Technology, United States, SIM

NMIA

National Measurement Institute, Australia, Australia, APMP

NMIJ AIST

National Metrology Institute of Japan, Japan, APMP

NMISA

National Metrology Institute of South Africa, South Africa, AFRIMETS

NML-SIRIM

National Metrology Laboratory, SIRIM Berhad (became NMIM), Malaysia, APMP

NRC

National Research Council, Canada, SIM

UME

TÜBITAK Ulusal Metroloji Enstitüsü, Türkiye, EURAMET

VNIIM

D.I. Mendeleyev Institute for Metrology, Rosstandart, Russian Federation, COOMET

MEASURAND : Mass fraction of Valine in the CCQM-K55.c samples

The key comparison reference value for the mass fraction of valine, xR, was calculated by substraction from the limit value of 1000 mg/g of the summation of the individual estimates for each contributing class of impurities present in CCQM-K55.c samples, as explained in page 23 of the Final Report. Its standard uncertainty, uR, is computed by combination in quadrature of the uncertainties associated with each contributing impurity estimate and also uncertainties in the inter-unit homogeneity of related substance impurity content.

xR = 992.0 mg/g, uR = 0.3 mg/g
 

The degree of equivalence of laboratory i with respect to the key comparison reference value is given by a pair of terms: Di = (xi - xR) and Ui, its expanded uncertainty (k = 2), both expressed in mg/g, with Ui = 2(ui2 + uR2)1/2.
No pair-wise degrees of equivalence are computed for this comparison.

MEASURAND : Mass fraction of Related Structure Impurities in the CCQM-K55.c samples

Key comparison reference values (xR) and associated standard uncertainty (uR) were assigned for the mass fraction of each orthogonal impurity class -  related substances, water, volatile organics and non-volatiles - quantified by the participants in CCQM-K55.c who used a mass balance approach to assign the valine content. They are consensus values derived from the individual data supplied by each participant. The assignment method varied by impurity class and each is separately described on pages 11 to page 18 of the Final Report.

For Total Related Structure Impurities, xR = 7.60 mg/g, uR = 0.24 mg/g
 

The degree of equivalence of laboratory i with respect to the key comparison reference value is given by a pair of terms: Di = (xi - xR) and Ui, its expanded uncertainty (k = 2), both expressed in mg/g, with Ui = 2(ui2 + uR2)1/2.
No pair-wise degrees of equivalence are computed for this comparison.

MEASURAND : Mass fraction of Water in the CCQM-K55.c samples

Key comparison reference values (xR) and associated standard uncertainty (uR) were assigned for the mass fraction of each orthogonal impurity class - related substances, water, volatile organics and non-volatiles - quantified by the participants in CCQM-K55.c who used a mass balance approach to assign the valine content. They are consensus values derived from the individual data supplied by each participant. The assignment method varied by impurity class and each is separately described on pages 11 to page 18 of the Final Report.

For Water, xR = 0.155 mg/g, uR = 0.042 mg/g
 

The degree of equivalence of laboratory i with respect to the key comparison reference value is given by a pair of terms: Di = (xi - xR) and Ui, its expanded uncertainty (k = 2), both expressed in mg/g, with Ui = 2(ui2 + uR2)1/2.
No pair-wise degrees of equivalence are computed for this comparison.

MEASURAND : Mass fraction of Volatile Organics in the CCQM-K55.c samples

Key comparison reference values (xR) and associated standard uncertainty (uR) were assigned for the mass fraction of each orthogonal impurity class - related substances, water, volatile organics and non-volatiles - quantified by the participants in CCQM-K55.c who used a mass balance approach to assign the valine content. They are consensus values derived from the individual data supplied by each participant. The assignment method varied by impurity class and each is separately described on pages 11 to page 18 of the Final Report.

For Volatile Organics, xR = 0.0 mg/g, uR+ = 0.12 mg/g, uR- = 0.0 mg/g
 

The degree of equivalence of laboratory i with respect to the key comparison reference value is given by a pair of terms: Di = (xi - xR) and Ui, its expanded uncertainty (k = 2), both expressed in mg/g, with Ui = 2(ui2 + uR2)1/2.
No pair-wise degrees of equivalence are computed for this comparison.

MEASURAND : Mass fraction of Non-Volatile Content in the CCQM-K55.c samples

Key comparison reference values (xR) and associated standard uncertainty (uR) were assigned for the mass fraction of each orthogonal impurity class - related substances, water, volatile organics and non-volatiles - quantified by the participants in CCQM-K55.c who used a mass balance approach to assign the valine content. They are consensus values derived from the individual data supplied by each participant. The assignment method varied by impurity class and each is separately described on pages 11 to page 18 of the Final Report.

For Non-Volatiles, xR = 0.25 mg/g, uR = 0.144 mg/g
 

The degree of equivalence of laboratory i with respect to the key comparison reference value is given by a pair of terms: Di = (xi - xR) and Ui, its expanded uncertainty (k = 2), both expressed in mg/g, with Ui = 2(ui2 + uR2)1/2.
No pair-wise degrees of equivalence are computed for this comparison.

MEASURAND : Mass fraction of Valine in the CCQM-K55.c samples

xi : result of measurement carried out by laboratory i
ui : combined standard uncertainty of xi

MEASURAND : Mass fraction of Related Structure Impurities in the CCQM-K55.c samples

xi : result of measurement carried out by laboratory i
ui : combined standard uncertainty of xi

MEASURAND : Mass fraction of Water in the CCQM-K55.c samples

xi : result of measurement carried out by laboratory i
ui : combined standard uncertainty of xi

MEASURAND : Mass fraction of Volatile Organics in the CCQM-K55.c samples

xi : result of measurement carried out by laboratory i
ui : combined standard uncertainty of xi

MEASURAND : Mass fraction of Non-Volatile Content in the CCQM-K55. c samples

xi : result of measurement carried out by laboratory i
ui : combined standard uncertainty of xi